Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.67 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.67 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.67 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.67 |
| ▸ | F2 | P00734 | 1/20 | 0.67 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.65 |
| ▸ | PKM | P14618 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.62 |
| ▸ | CA12 | O43570 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | PLG | P00747 | 1/20 | 0.57 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | IDE | P14735 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31135780 | 1.00 | PRSS1 (0.67) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL24425712 | 1.00 | PRSS1 (0.67) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL19917580 | 0.97 | PRSS1 (0.63) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL4922024 | 0.95 | TDP1 (0.64) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL19751698 | 0.94 | F2 (0.73) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL15216220 | 0.94 | F2 (0.73) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL19017236 | 0.94 | F2 (0.73) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL4968230 | 0.94 | F2 (0.73) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL15832044 | 0.93 | PKM (0.69) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL21531148 | 0.91 | FOLH1 (0.67) | PRSS1PRSS2PRSS3TPSAB1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11897874-B2 | Compounds and methods for modulating Interleukin-2-inducible T-cell kinase | CORVUS PHARMACEUTICALS, INC. (US) | 2024-02-13 | — | — | US | disclosed |
| EP-2535423-B1 | Labeling and detection of nucleic acids | LIFE TECHNOLOGIES CORP (US) | 2019-05-15 | — | — | EP | disclosed |
| EP-2623986-B1 | Labeling and detection of post translationally modified proteins | LIFE TECHNOLOGIES CORP (US) | 2017-06-14 | — | — | EP | disclosed |
| US-8957056-B2 | Migrastatin analogs in the treatment of cancer | SLOAN-KETTERING INSTIUTE FOR CANCER RESEARCH (US) | 2015-02-17 | — | — | US | disclosed |
| US-8835693-B2 | Migrastatin analogs and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2014-09-16 | — | — | US | disclosed |
| US-20140011844-A1 | MIGRASTATIN ANALOGS AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2014-01-09 | — | — | US | disclosed |
| US-8324284-B2 | Migrastatin analogs and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2012-12-04 | — | — | US | disclosed |
| US-8202911-B2 | Migrastatin analog compositions and uses thereof | CORNELL RESEARCH FOUNDATION, INC. (US) | 2012-06-19 | — | — | US | disclosed |
| US-20110263653-A1 | MIGRASTATIN ANALOG COMPOSITIONS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-10-27 | — | — | US | disclosed |
| US-7943800-B2 | Migrastatin analogs and uses thereof | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2011-05-17 | — | — | US | disclosed |
| WO-2011006143-A2 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES | IRM LLC (BM) | 2011-01-13 | — | — | WO | disclosed |
| US-20090124662-A1 | Migrastatin analogs in the treatment of cancer | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | 2009-05-14 | — | — | US | disclosed |
| US-20070037852-A1 | Migrastatin analogs and uses thereof | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2007-02-15 | — | — | US | disclosed |
| US-20070037783-A1 | Migrastatin analogs and uses thereof | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037783-A1 | Migrastatin analogs and uses thereof | FOXM1, MTX1, C3AR1 | PRSS1 1602/4885PRSS2 1692/4885PRSS3 1948/4885 |
| US-20090124662-A1 | Migrastatin analogs in the treatment of cancer | MTX1, MTNR1B, MTNR1A | PRSS1 767/4885PRSS2 880/4885PRSS3 1119/4885 |
| US-20110263653-A1 | MIGRASTATIN ANALOG COMPOSITIONS AND USES THEREOF | C3AR1, C1R, MRPS18A | PRSS1 1954/4885PRSS2 2018/4885PRSS3 2142/4885 |
| US-11897874-B2 | Compounds and methods for modulating Interleukin-2-inducible T-cell kinase | IL2, NFATC1, IL2RA | PRSS1 3218/4885PRSS2 2869/4885PRSS3 4319/4885 |
| US-20070037852-A1 | Migrastatin analogs and uses thereof | KDR, MTX1, FOXM1 | PRSS1 1384/4885PRSS2 2369/4885PRSS3 2526/4885 |
| US-20140011844-A1 | MIGRASTATIN ANALOGS AND USES THEREOF | KDR, HMGCR, LPAR3 | PRSS1 1523/4885PRSS2 2446/4885PRSS3 2602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.