Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNI3K | Q59H18 | 12/20 | 0.44 |
| ▸ | BRAF | P15056 | 6/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9980393 | 0.87 | TNNI3K (0.40) | TNNI3KBRAFEGFR | |
| SCHEMBL9986097 | 0.75 | TNNI3K (0.73) | TNNI3KBRAF | |
| SCHEMBL1806649 | 0.75 | BRAF (0.59) | TNNI3KBRAFEGFR | |
| SCHEMBL1804094 | 0.73 | BRAF (0.60) | TNNI3KBRAFSLC6A4SLC6A3SLC6A2 | |
| SCHEMBL1806890 | 0.73 | BRAF (0.59) | TNNI3KBRAFEGFR | |
| SCHEMBL1805553 | 0.73 | BRAF (0.59) | TNNI3KBRAFEGFR | |
| SCHEMBL2229060 | 0.72 | SLC6A4 (0.46) | TNNI3KSLC6A4SLC6A3SLC6A2EGFR | |
| SCHEMBL12067916 | 0.72 | TNNI3K (0.62) | TNNI3KBRAF | |
| SCHEMBL1809417 | 0.72 | BRAF (0.60) | TNNI3KBRAFEGFR | |
| SCHEMBL12067874 | 0.71 | TNNI3K (0.63) | TNNI3KBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011149827-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2011-12-01 | — | — | WO | disclosed |