SCHEMBL9980773

SCHEMBL9980773

CCC1C(=O)NC(=O)N(c2ccccc2)C1=O

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.57
MAPT P10636 3/20 0.57
HSD17B10 Q99714 1/20 0.57
KDM4C Q9H3R0 1/20 0.57
SMN1; SMN2 Q16637 2/20 0.48
LMNA P02545 2/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
GAA P10253 3/20 0.48
CES2 O00748 1/20 0.48
ELANE P08246 2/20 0.46
CACNA1B Q00975 1/20 0.42
APBA1 Q02410 1/20 0.42
ADORA3 P0DMS8 1/20 0.41
ALOX5 P09917 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.41
MAOA P21397 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17717930 0.86 ALDH1A1 (0.53) ALDH1A1MAPTHSD17B10KDM4CSMN1; SMN2
SCHEMBL11741035 0.86 GAA (0.51) ALDH1A1MAPTHSD17B10KDM4CSMN1; SMN2
SCHEMBL17358727 0.82 CES2 (0.49) ALDH1A1MAPTHSD17B10KDM4CSMN1; SMN2
SCHEMBL17717951 0.82 ALDH1A1 (0.60) ALDH1A1MAPTHSD17B10KDM4CSMN1; SMN2
SCHEMBL17717928 0.82 ALDH1A1 (0.50) ALDH1A1MAPTHSD17B10KDM4CSMN1; SMN2
SCHEMBL472396 0.82 ALDH1A1 (0.56) ALDH1A1MAPTHSD17B10KDM4CSMN1; SMN2
SCHEMBL17717943 0.81 MAPT (0.58) ALDH1A1MAPTHSD17B10KDM4CSMN1; SMN2
SCHEMBL17358733 0.80 ALDH1A1 (0.48) ALDH1A1MAPTHSD17B10KDM4CSMN1; SMN2
SCHEMBL2364824 0.80 CES2 (0.51) ALDH1A1MAPTHSD17B10KDM4CSMN1; SMN2
SCHEMBL17358737 0.79 ALDH1A1 (0.57) ALDH1A1MAPTHSD17B10KDM4CSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2630976-B1 Bone cement in paste form HERAEUS MEDICAL GMBH (DE) 2017-09-20 EP claimed
EP-2550980-B1 Bone cement in paste form HERAEUS MEDICAL GMBH (DE) 2017-09-20 EP claimed
CN-103251977-B The bone cement of pasty state HERAEUS MEDICAL GMBH (DE) 2016-06-01 CN claimed
US-9018277-B2 Paste-like bone cement HERAEUS MEDICAL GMBH (DE) 2015-04-28 US claimed
CN-103223189-B Bone cement in paste form HERAEUS MEDICAL GMBH 2015-02-25 CN claimed
US-20130281566-A1 Paste-Like Bone Cement HERAEUS MEDICAL GMBH (DE) 2013-10-24 US claimed
CN-103251977-A Paste-like bone cement HERAEUS MEDICAL GMBH 2013-08-21 CN claimed
CN-103223189-A Bone cement in paste form HERAEUS MEDICAL GMBH 2013-07-31 CN claimed
US-20130158158-A1 Paste-Like Bone Cement HERAEUS MEDICAL GMBH (DE) 2013-06-20 US claimed
CN-107569715-B Antibacterial polymethylmethacrylate bone cement 贺利氏医疗有限责任公司 2020-12-04 CN disclosed
CN-107029278-B Antibacterial polymethylmethacrylate bone cement 贺利氏医疗有限责任公司 2020-12-01 CN disclosed
US-20190314546-A1 ANTIBIOTIC POLYMETHYLMETHACRYLATE BONE CEMENT HERAEUS MEDICAL GMBH (DE) 2019-10-17 US disclosed
US-10322207-B2 Antiseptic polymethylmethacrylate bone cement HERAEUS MEDICAL GMBH (DE) 2019-06-18 US disclosed
US-10293078-B2 Polymethylmethacrylate bone cement with adjustable initial viscosity, and method for producing a bone cement dough with variable initial viscosity HERAEUS MEDICAL GMBH (DE) 2019-05-21 US disclosed
CN-103223189-A Bone cement in paste form HERAEUS MEDICAL GMBH 2013-07-31 CN disclosed
CN-103223188-A Paste-like bone cement HERAEUS MEDICAL GMBH 2013-07-31 CN disclosed
US-20130158158-A1 Paste-Like Bone Cement HERAEUS MEDICAL GMBH (DE) 2013-06-20 US disclosed
US-20130030058-A1 KIT AND METHOD FOR PRODUCING BONE CEMENT HERAEUS MEDICAL GMBH (DE) 2013-01-31 US disclosed
CN-102327642-A The pasty state bone cement HERAEUS MEDICAL GMBH 2012-01-25 CN disclosed
US-20110313078-A1 PASTE-LIKE BONE CEMENT HERAEUS MEDICAL GMBH (DE) 2011-12-22 US disclosed