Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.46 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.46 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 3/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9980777 | 1.00 | ELANE (0.46) | ELANETPSAB1TPSD1TPSG1KMT2A | |
| SCHEMBL9980739 | 0.92 | ELANE (0.44) | ELANETPSAB1TPSD1TPSG1KMT2A | |
| SCHEMBL9980737 | 0.92 | ELANE (0.44) | ELANETPSAB1TPSD1TPSG1KMT2A | |
| SCHEMBL9980936 | 0.79 | ALDH1A1 (0.40) | KMT2AMAPTMEN1ALDH1A1LMNA | |
| SCHEMBL9980934 | 0.79 | ALDH1A1 (0.40) | KMT2AMAPTMEN1ALDH1A1LMNA | |
| SCHEMBL12027097 | 0.75 | GAA (0.45) | ELANEKMT2ARAB9AGAAPOLB | |
| SCHEMBL12027035 | 0.75 | GAA (0.45) | ELANEKMT2ARAB9AGAAPOLB | |
| SCHEMBL9980820 | 0.75 | RAB9A (0.51) | ELANEKMT2ARAB9AGAAMAPT | |
| SCHEMBL14678651 | 0.74 | RAB9A (0.56) | ELANETPSAB1TPSD1TPSG1KMT2A | |
| SCHEMBL9987125 | 0.74 | ALDH1A1 (0.44) | KMT2APOLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8486534-B2 | Surface-modified polymer films | BAR-ILAN UNIVERSITY (IL) | 2013-07-16 | — | — | US | disclosed |
| US-20110306722-A1 | SURFACE-MODIFIED POLYMER FILMS | BAR-ILAN UNIVERSITY (IL) | 2011-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110306722-A1 | SURFACE-MODIFIED POLYMER FILMS | PARN, ITGAM, PARG | ELANE 573/4885TPSAB1 3455/4885TPSD1 3384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.