Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 2/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9980787 | 1.00 | NPC1 (0.49) | NPC1RAB9ALMNAMAPTALDH1A1 | |
| SCHEMBL12027039 | 0.89 | NPC1 (0.41) | NPC1RAB9ALMNAMAPTALDH1A1 | |
| SCHEMBL12027098 | 0.89 | NPC1 (0.41) | NPC1RAB9ALMNAMAPTALDH1A1 | |
| SCHEMBL9980811 | 0.89 | RAB9A (0.51) | NPC1RAB9ALMNAMAPTALDH1A1 | |
| SCHEMBL9980820 | 0.89 | RAB9A (0.51) | NPC1RAB9ALMNAMAPTALDH1A1 | |
| SCHEMBL15107105 | 0.85 | DNM1 (0.38) | NPC1RAB9AFNTAFNTBESR1 | |
| SCHEMBL12027035 | 0.78 | GAA (0.45) | NPC1RAB9ALMNAMAPTALDH1A1 | |
| SCHEMBL12027097 | 0.78 | GAA (0.45) | NPC1RAB9ALMNAMAPTALDH1A1 | |
| SCHEMBL9980737 | 0.76 | ELANE (0.44) | RAB9AMAPTALDH1A1MEN1HPGD | |
| SCHEMBL9980739 | 0.76 | ELANE (0.44) | RAB9AMAPTALDH1A1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8486534-B2 | Surface-modified polymer films | BAR-ILAN UNIVERSITY (IL) | 2013-07-16 | — | — | US | disclosed |
| US-20110306722-A1 | SURFACE-MODIFIED POLYMER FILMS | BAR-ILAN UNIVERSITY (IL) | 2011-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110306722-A1 | SURFACE-MODIFIED POLYMER FILMS | PARN, ITGAM, PARG | NPC1 4360/4885RAB9A 3562/4885LMNA 1592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.