Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 13/20 | 1.00 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1048281 | 0.88 | NAMPT (1.00) | NAMPTTRPV1LMNANPC1RAB9A | |
| SCHEMBL16286298 | 0.87 | MEN1 (0.81) | NAMPTLMNAGAAMEN1KMT2A | |
| SCHEMBL12078582 | 0.87 | NAMPT (0.84) | NAMPTTRPV1GAAMEN1KMT2A | |
| SCHEMBL167081 | 0.86 | NAMPT (1.00) | NAMPTLMNANPC1RAB9AGAA | |
| SCHEMBL995725 | 0.85 | NAMPT (1.00) | NAMPT | |
| Hydrochloric Acid SCHEMBL27890956 | 0.84 | NAMPT (0.97) | NAMPTLMNANPC1RAB9AGAA | |
| SCHEMBL12078119 | 0.83 | LMNA (0.79) | NAMPTTRPV1LMNARAB9AGAA | |
| SCHEMBL1078768 | 0.82 | NAMPT (1.00) | NAMPTTRPV1MEN1KMT2A | |
| SCHEMBL354041 | 0.82 | TSHR (0.76) | NAMPTNPC1RAB9AGAAMEN1 | |
| SCHEMBL1161997 | 0.82 | NAMPT (0.75) | NAMPTTRPV1LMNAGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011514-A1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-01-27 | — | — | WO | claimed |
| WO-2011011514-A1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-01-27 | — | — | WO | disclosed |