Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL999633 | 0.85 | ALDH1A1 (0.68) | ALDH1A1LMNAMMP2TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL998382 | 0.83 | ALDH1A1 (0.66) | ALDH1A1LMNAMMP2TSHRTDP1 | |
| SCHEMBL13516157 | 0.81 | ALDH1A1 (0.54) | ALDH1A1LMNAMMP2TSHRTDP1 | |
| SCHEMBL2143864 | 0.81 | ALDH1A1 (0.73) | ALDH1A1LMNAMMP2TSHRTDP1 | |
| SCHEMBL1164312 | 0.79 | PARP1 (0.68) | ALDH1A1LMNAMMP2TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL5126803 | 0.77 | PARP1 (0.66) | ALDH1A1LMNAMMP2TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL30615213 | 0.77 | PARP1 (0.66) | ALDH1A1LMNAMMP2TSHRTDP1 | |
| SCHEMBL27908517 | 0.77 | TDP1 (0.48) | ALDH1A1LMNAMMP2TSHRTDP1 | |
| SCHEMBL9296152 | 0.75 | L3MBTL1 (0.54) | ALDH1A1LMNAMMP2TSHRTDP1 | |
| SCHEMBL16861478 | 0.73 | KMT2A (0.51) | ALDH1A1TDP1KDM4ETP53HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2456759-B1 | PESTICIDAL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2017-04-19 | — | — | EP | disclosed |
| US-8822691-B2 | Pesticidal carboxamides | BAYER CROPSCIENCE AG (DE) | 2014-09-02 | — | — | US | disclosed |
| US-20120277185-A1 | Pesticidal Carboxamides | BAYER CROPSCIENDE AG (DE) | 2012-11-01 | — | — | US | disclosed |
| CN-102548967-A | Pesticidal carboxamides | BAYER CROPSCIENCE AG | 2012-07-04 | — | — | CN | disclosed |
| EP-2456759-A2 | PESTICIDAL CARBOXAMIDES | Bayer CropScience AG (DE) | 2012-05-30 | — | — | EP | disclosed |
| WO-2011009540-A2 | PESTICIDAL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2011-01-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120277185-A1 | Pesticidal Carboxamides | DDT, ACHE, AADAC | ALDH1A1 1266/4885LMNA 3905/4885MMP2 1119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.