Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL9837086 | 0.96 | — | — | |
| Guanidine SCHEMBL6529286 | 0.85 | — | — | |
| Guanidine SCHEMBL6708027 | 0.85 | CA1 (0.33) | — | |
| 2-Mercaptoethanol SCHEMBL15541338 | 0.79 | — | — | |
| Guanidine SCHEMBL2634404 | 0.79 | — | — | |
| 2-Mercaptoethanol SCHEMBL5702 | 0.78 | — | — | |
| 2-Mercaptoethanol SCHEMBL3727625 | 0.78 | — | — | |
| Urea SCHEMBL9750925 | 0.77 | ALDH1A1 (0.46) | — | |
| Urea SCHEMBL514134 | 0.77 | — | — | |
| 2-Mercaptoethanol SCHEMBL11130898 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011008553-A1 | RNA SAMPLE STABILIZATION IN THE PRESENCE OF A TRANSITIONAL METAL | Life Technologies Corporation (US) | 2011-01-20 | — | — | WO | disclosed |