Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | INMT | O95050 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 2/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251940 | 0.95 | CYP2D6 (0.42) | CYP2D6CYP3A4CYP2C19USP2INMT | |
| SCHEMBL2740903 | 0.91 | CYP2D6 (0.42) | CYP2D6CYP3A4CYP2C19USP2INMT | |
| SCHEMBL252415 | 0.84 | CYP2D6 (0.44) | CYP2D6CYP3A4CYP2C19USP2INMT | |
| SCHEMBL8368647 | 0.83 | ALDH1A1 (0.45) | CYP2D6CYP3A4CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL253401 | 0.81 | ALDH1A1 (0.47) | CYP2D6CYP3A4CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL17217520 | 0.81 | ALDH1A1 (0.47) | CYP2D6CYP3A4CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL31066868 | 0.81 | ALDH1A1 (0.47) | CYP2D6CYP3A4CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL31066883 | 0.81 | ALDH1A1 (0.47) | CYP2D6CYP3A4CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL31066870 | 0.81 | ALDH1A1 (0.47) | CYP2D6CYP3A4CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL250783 | 0.81 | ALDH1A1 (0.47) | CYP2D6CYP3A4CYP2C19CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1930376-B2 | CURABLE COMPOSITION | KANEKA CORP (JP) | 2016-09-07 | — | — | EP | disclosed |
| WO-2012036392-A3 | HUMAN ANTI-EPIDERMAL GROWTH FACTOR RECEPTOR FAB ANTIBODY AND A PHARMACEUTICAL COMPOSITION FOR TREATING TUMOURS COMPRISING THE SAME | 주식회사 아이지세라피 (KR) | 2012-05-10 | — | — | WO | disclosed |
| EP-1930376-B1 | CURABLE COMPOSITION | KANEKA CORP (JP) | 2011-12-07 | — | — | EP | disclosed |