SCHEMBL9985366

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9984898	0.90	MAPT (0.48)	TSHRALDH1A1MAPTMEN1KMT2A
	SCHEMBL9984469	0.86	ALDH1A1 (0.47)	ALDH1A1MAPTMEN1KMT2APOLB
	SCHEMBL9985086	0.81	BRD4 (0.47)	ALDH1A1MAPTMEN1KMT2APOLB
	SCHEMBL9984361	0.80	HSF1 (0.55)	ALDH1A1MAPTMEN1KMT2APOLB
	SCHEMBL9984038	0.79	PLK1 (0.50)	ALDH1A1MAPTMEN1KMT2ACDK5
	SCHEMBL9984953	0.78	BRD4 (0.45)	ALDH1A1MAPTMEN1KMT2APOLB
	SCHEMBL6793673	0.78	HSF1 (0.65)	ALDH1A1MAPTCDK5CDK5R1HTT
	SCHEMBL6783868	0.78	HSF1 (0.55)	ALDH1A1MAPTPOLBCDK5CDK5R1
	SCHEMBL9984677	0.78	BRD4 (0.60)	ALDH1A1MAPTMEN1KMT2APOLB
	SCHEMBL9985368	0.77	ALDH1A1 (0.45)	TSHRALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.