SCHEMBL998560

SCHEMBL998560

CN(C)c1cccc2ccccc12.O=S(=O)(Cl)Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.52
CA2 P00918 1/20 0.51
MCL1 Q07820 1/20 0.49
KDM4E B2RXH2 2/20 0.47
MAPT P10636 2/20 0.47
GAA P10253 1/20 0.47
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C19 P33261 1/20 0.46
HTT P42858 1/20 0.46
HIF1A Q16665 1/20 0.46
CHEK1 O14757 1/20 0.46
NEK2 P51955 1/20 0.46
LIMK1 P53667 1/20 0.46
DYRK1A Q13627 1/20 0.46
CLK4 Q9HAZ1 1/20 0.46
HTR6 P50406 3/20 0.45
EDNRA P25101 2/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8450705 0.93 SIGMAR1 (0.53) SIGMAR1CA2MCL1KDM4EMAPT
Acetonitrile SCHEMBL28781304 0.92 CA2 (0.45) SIGMAR1CA2MCL1KDM4EMAPT
Sulfamide SCHEMBL3360909 0.89 CA2 (0.61) SIGMAR1CA2MCL1KDM4EMAPT
SCHEMBL29364795 0.88 SIGMAR1 (0.63) SIGMAR1CA2MCL1KDM4EMAPT
SCHEMBL29555314 0.88 SIGMAR1 (0.63) SIGMAR1CA2MCL1KDM4EMAPT
SCHEMBL27737084 0.88 SIGMAR1 (0.63) SIGMAR1CA2MCL1KDM4EMAPT
SCHEMBL2349 0.88 SIGMAR1 (0.63) SIGMAR1CA2MCL1KDM4EMAPT
Hydrochloric Acid SCHEMBL2866027 0.86 SIGMAR1 (0.61) SIGMAR1CA2MCL1KDM4EMAPT
Hydrochloric Acid SCHEMBL31515359 0.86 SIGMAR1 (0.61) SIGMAR1CA2MCL1KDM4EMAPT
Hydrogen Sulfide SCHEMBL3359211 0.86 SIGMAR1 (0.61) SIGMAR1CA2MCL1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117607117-A Visual research method for reaction property of lipase at oil-water interface 四川大学 2024-02-27 CN claimed
CN-117466906-A Oridonin derivative, preparation method thereof, pharmaceutical composition and application 中国人民解放军海军军医大学 2024-01-30 CN claimed
CN-108760950-B Method for determining nitrofuran metabolite 国检测试控股集团京诚检测有限公司 2022-07-15 CN claimed
CN-104678028-A Pretreatment and detection method for biogen amine neurotransmitter and detection kit INST PHARM & TOXICOLOGY AMMS 2015-06-03 CN claimed
CN-116875690-B Gene mutation for diagnosing multiple epiphyseal dysplasia BEIJING RESEARCH INSTITUTE OF TRAUMATOLOGY AND ORTHOPAEDICS (CN) 2026-05-26 CN disclosed
CN-117630263-A Method for detecting various free amino acids in plasma based on liquid chromatography-tandem mass spectrometry 上海睿质科技有限公司 2024-03-01 CN disclosed
CN-117607117-A Visual research method for reaction property of lipase at oil-water interface 四川大学 2024-02-27 CN disclosed
CN-117466906-A Oridonin derivative, preparation method thereof, pharmaceutical composition and application 中国人民解放军海军军医大学 2024-01-30 CN disclosed
CN-116875690-A Gene mutation for diagnosing multiple epiphyseal dysplasia 北京市创伤骨科研究所 2023-10-13 CN disclosed
WO-2023150778-A1 ANTI-IDIOTYPE ANTIBODY MOLECULES AND USES THEREOF Visterra, Inc. (US) 2023-08-10 WO disclosed
WO-2023097254-A1 ENGINEERED ANTIBODY MOLECULES TO CD138 AND USES THEREOF Visterra, Inc. (US) 2023-06-01 WO disclosed
US-20230160807-A1 Integrated Flow Cytometry Data Quality Control BECTON, DICKINSON AND COMPANY 2023-05-25 US disclosed
EP-0557350-B1 ASSAY FOR GLYCATED BLOOD PROTEINS AXIS BIOCHEMICALS AS (NO) 1994-10-05 EP disclosed
US-5242842-A Precipitation AXIS RESEARCH AS (NO) 1993-09-07 US disclosed
EP-0557350-A1 ASSAY FOR GLYCATED BLOOD PROTEINS. AXIS RESEARCH (NO) 1993-09-01 EP disclosed
WO-1992008984-A1 ASSAY FOR GLYCATED BLOOD PROTEINS AXIS RESEARCH AS (NO) 1992-05-29 WO disclosed
EP-0471774-A1 GLYCOSYLATED HAEMOGLOBIN ASSAY. AXIS RESEARCH (NO) 1992-02-26 EP disclosed
WO-1990013818-A1 GLYCOSYLATED HAEMOGLOBIN ASSAY AXIS RESEARCH AS (NO) 1990-11-15 WO disclosed
US-4672044-A Murine monoclonal antibody combining site to human C3b receptor (CR1) SCRIPPS CLINIC & RESEARCH FOUNDATION (US) 1987-06-09 US disclosed
US-4231750-A Methods for performing chemical assays using fluorescence and photon counting DIAGNOSTIC REAGENTS, INC. (US) 1980-11-04 US disclosed