Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15466547 | 0.88 | ALDH1A1 (0.55) | ALDH1A1KDM4EHTTMAPTLMNA | |
| SCHEMBL28767719 | 0.87 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTLMNAPOLB | |
| SCHEMBL30268631 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4EHTTMAPTLMNA | |
| SCHEMBL28369297 | 0.82 | PSEN1 (0.55) | ALDH1A1KDM4EHTTMAPTMAPK1 | |
| SCHEMBL28369488 | 0.82 | PSEN1 (0.55) | ALDH1A1KDM4EHTTMAPTMAPK1 | |
| SCHEMBL28374675 | 0.82 | PSEN1 (0.55) | ALDH1A1KDM4EHTTMAPTMAPK1 | |
| SCHEMBL14208786 | 0.81 | ALDH1A1 (0.59) | ALDH1A1KDM4EHTTMAPTLMNA | |
| SCHEMBL29139893 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4EHTTMAPTLMNA | |
| SCHEMBL17885720 | 0.80 | ALDH1A1 (0.53) | ALDH1A1KDM4EHTTMAPTLMNA | |
| SCHEMBL1001712 | 0.80 | LIPG (0.44) | ALDH1A1KDM4EHTTMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003089-B | 3-hydroxymethyl-9-substituted carbazole and preparation method thereof | 陕西科技大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-110759852-A | Preparation method of 3-hydroxymethyl-9-substituted carbazole | 陕西科技大学 | 2020-02-07 | — | — | CN | disclosed |
| US-8080566-B1 | Carbazole inhibitors of histamine receptors for the treatment of disease | KALYPSYS, INC (US) | 2011-12-20 | — | — | US | disclosed |