Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 18/20 | 0.73 |
| ▸ | CYP11B1 | P15538 | 17/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | ROS1 | P08922 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14848543 | 1.00 | CYP11B2 (0.73) | CYP11B2CYP11B1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9984894 | 0.90 | CYP11B2 (0.75) | CYP11B2CYP11B1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12027214 | 0.86 | CYP11B2 (0.73) | CYP11B2CYP11B1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9984093 | 0.86 | CYP11B2 (0.73) | CYP11B2CYP11B1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3004402 | 0.84 | CYP11B2 (1.00) | CYP11B2CYP11B1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12027311 | 0.75 | CYP11B2 (0.76) | CYP11B2CYP11B1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10458381 | 0.73 | CA12 (0.59) | — | |
| SCHEMBL7413835 | 0.73 | CYP11B2 (0.78) | CYP11B2CYP11B1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4509505 | 0.73 | CYP11B2 (0.72) | CYP11B2CYP11B1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3268274 | 0.72 | CYP1A2 (0.52) | CYP11B2CYP11B1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130089502-A1 | PET RADIOPHARMACEUTICALS FOR DIFFERENTIAL DIAGNOSIS BETWEEN BILATERAL AND UNILATERAL CONDITIONS OF PRIMARY HYPERALDOSTERONISM | UNIVERSITAT DES SAARLANDES (DE) | 2013-04-11 | — | — | US | disclosed |
| US-20130089502-A1 | PET RADIOPHARMACEUTICALS FOR DIFFERENTIAL DIAGNOSIS BETWEEN BILATERAL AND UNILATERAL CONDITIONS OF PRIMARY HYPERALDOSTERONISM | UNIVERSITAT DES SAARLANDES (DE) | 2013-04-11 | — | — | US | disclosed |
| US-20130089502-A1 | PET RADIOPHARMACEUTICALS FOR DIFFERENTIAL DIAGNOSIS BETWEEN BILATERAL AND UNILATERAL CONDITIONS OF PRIMARY HYPERALDOSTERONISM | UNIVERSITAT DES SAARLANDES (DE) | 2013-04-11 | — | — | US | disclosed |
| EP-2575899-A1 | PET RADIOPHARMACEUTICALS FOR DIFFERENTIAL DIAGNOSIS BETWEEN BILATERAL AND UNILATERAL CONDITIONS OF PRIMARY HYPERALDOSTERONISM | Julius-Maximilians-Universität Würzburg (DE) | 2013-04-10 | — | — | EP | disclosed |
| EP-2394668-A1 | PET radiopharmaceuticals for differential diagnosis between bilateral and unilateral conditions of primary hyperaldosteronism | Julius-Maximilians-Universität Würzburg (DE) | 2011-12-14 | — | — | EP | disclosed |
| WO-2011151411-A1 | PET RADIOPHARMACEUTICALS FOR DIFFERENTIAL DIAGNOSIS BETWEEN BILATERAL AND UNILATERAL CONDITIONS OF PRIMARY HYPERALDOSTERONISM | JULIUS-MAXIMILIANS-UNIVERSITÄT (DE) | 2011-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130089502-A1 | PET RADIOPHARMACEUTICALS FOR DIFFERENTIAL DIAGNOSIS BETWEEN BILATERAL AND UNILATERAL CONDITIONS OF PRIMARY HYPERALDOSTERONISM | HSD11B1, HSD11B2, CYP11B1 | CYP11B2 4/4885CYP11B1 3/4885CYP1A2 31/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.