Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | SORD | Q00796 | 1/20 | 0.44 |
| ▸ | DKK1 | O94907 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | HCK | P08631 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1742937 | 0.81 | GPR119 (0.43) | ACHEPIK3CAPIK3CDPIK3CBABL1 | |
| SCHEMBL1744087 | 0.78 | RET (0.39) | PIK3CAPIK3CDPIK3CBABL1EGFR | |
| SCHEMBL15344920 | 0.70 | SORD (0.59) | ACHESORDHRH3 | |
| SCHEMBL15341759 | 0.69 | ACHE (0.54) | ACHESORDPANK3HRH3 | |
| SCHEMBL17671346 | 0.68 | KDM4E (0.52) | ACHE | |
| SCHEMBL18652300 | 0.68 | ACHE (0.51) | ACHESORDPANK3HRH3 | |
| SCHEMBL26748791 | 0.67 | ACHE (0.52) | ACHESORD | |
| SCHEMBL17310242 | 0.66 | OGA (0.60) | ACHESORDHRH3 | |
| SCHEMBL13677029 | 0.65 | OGA (0.65) | ACHESORD | |
| SCHEMBL5962506 | 0.65 | OGA (0.54) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2233470-B1 | Histamine H3 receptor antagonists | HIGH POINT PHARMACEUTICALS LLC (US) | 2011-12-07 | — | — | EP | disclosed |