Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RHOA | P61586 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | ROS1 | P08922 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9984165 | 0.93 | MAPT (0.44) | TDP1SERPINE1MAPTHTTALDH1A1 | |
| SCHEMBL9984257 | 0.91 | MAPT (0.41) | TDP1SERPINE1MAPTHTTALDH1A1 | |
| SCHEMBL9987425 | 0.91 | MAPT (0.44) | TDP1SERPINE1MAPTHTTALDH1A1 | |
| SCHEMBL9984371 | 0.90 | HTT (0.39) | TDP1SERPINE1MAPTHTTALDH1A1 | |
| SCHEMBL9984658 | 0.86 | MAPT (0.40) | TDP1SERPINE1MAPTHTTALDH1A1 | |
| SCHEMBL9984315 | 0.86 | MAPT (0.40) | TDP1SERPINE1MAPTHTTALDH1A1 | |
| SCHEMBL9987060 | 0.86 | TDP1 (0.43) | TDP1SERPINE1MAPTPOLBMAPK1 | |
| SCHEMBL9987376 | 0.85 | TDP1 (0.48) | TDP1SERPINE1MAPTPOLBMAPK1 | |
| SCHEMBL9984258 | 0.84 | MAPT (0.40) | TDP1SERPINE1MAPTHTTALDH1A1 | |
| SCHEMBL9987009 | 0.84 | L3MBTL1 (0.46) | TDP1SERPINE1MAPTHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2394993-A2 | NOVEL 2,6-SUBSTITUTED-3-NITROPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | Dong Wha Pharm. Co., Ltd. (KR) | 2011-12-14 | — | — | EP | disclosed |