Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | QPCT | Q16769 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 3/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | ROS1 | P08922 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9984101 | 0.94 | ALDH1A1 (0.45) | L3MBTL1ALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9984090 | 0.87 | ALDH1A1 (0.45) | L3MBTL1ALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9987164 | 0.84 | TDP1 (0.42) | L3MBTL1ALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9983509 | 0.83 | ALDH1A1 (0.42) | L3MBTL1ALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9987060 | 0.82 | TDP1 (0.43) | KMT2AMAPTMEN1MAPK1TDP1 | |
| SCHEMBL9987376 | 0.81 | TDP1 (0.48) | L3MBTL1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL9987013 | 0.81 | TDP1 (0.39) | TDP1SERPINE1JAK2BRD4RET | |
| SCHEMBL9987425 | 0.81 | MAPT (0.44) | ALDH1A1MAPTHTTTDP1SERPINE1 | |
| SCHEMBL9987584 | 0.79 | BRD4 (0.51) | L3MBTL1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL9987980 | 0.78 | TDP1 (0.49) | L3MBTL1KMT2AMAPTMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2394993-A2 | NOVEL 2,6-SUBSTITUTED-3-NITROPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | Dong Wha Pharm. Co., Ltd. (KR) | 2011-12-14 | — | — | EP | disclosed |