Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28402342 | 0.81 | SHBG (0.44) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL9717438 | 0.73 | EPHX1 (0.62) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL2985858 | 0.72 | SHBG (0.50) | EPHX1TP53SHBG | |
| SCHEMBL11838850 | 0.72 | SHBG (0.44) | EPHX1TP53LMNASHBGALDH1A1 | |
| SCHEMBL3001306 | 0.72 | SHBG (0.50) | EPHX1TP53SHBG | |
| SCHEMBL5065302 | 0.72 | SHBG (0.50) | EPHX1TP53SHBG | |
| SCHEMBL734472 | 0.72 | EPHX1 (0.54) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL3909022 | 0.72 | EPHX1 (0.42) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL3909020 | 0.72 | EPHX1 (0.42) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL4319269 | 0.72 | EPHX1 (0.42) | EPHX1TP53KDM4EGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2392400-B1 | Homogeneous asymmetric hydrogenation method | TAKASAGO PERFUMERY CO LTD (JP) | 2014-05-07 | — | — | EP | disclosed |
| EP-2392400-A2 | Homogeneous asymmetric hydrogenation catalyst | Takasago International Corporation (JP) | 2011-12-07 | — | — | EP | disclosed |