Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30234519 | 1.00 | MCL1 (0.45) | MCL1MTNR1AMTNR1BMEN1NPC1 | |
| SCHEMBL7873282 | 0.84 | MTNR1A (0.56) | MCL1MTNR1AMTNR1BKMT2ADAO | |
| SCHEMBL4445494 | 0.82 | MCL1 (0.62) | MCL1MTNR1AMTNR1BMEN1NPC1 | |
| SCHEMBL4102690 | 0.82 | PLA2G10 (0.49) | MCL1MTNR1AMTNR1BDAOALDH1A1 | |
| SCHEMBL29581946 | 0.79 | MCL1 (0.67) | MCL1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL1093913 | 0.79 | MCL1 (0.67) | MCL1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL2662561 | 0.78 | MCL1 (0.47) | MCL1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL9986961 | 0.77 | PLK1 (0.46) | MEN1KMT2AALDH1A1HPGDPOLB | |
| SCHEMBL2458550 | 0.76 | NOD2 (0.62) | MCL1MTNR1AMTNR1BMEN1NPC1 | |
| SCHEMBL5319827 | 0.75 | PPARG (0.54) | MTNR1AMTNR1BALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011163195-A1 | FUSED PYRROLE DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2011-12-29 | — | — | WO | disclosed |