Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.62 |
| ▸ | DAO | P14920 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CCR2 | P41597 | 4/20 | 0.51 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4102690 | 0.86 | PLA2G10 (0.49) | MCL1DAOALDH1A1TSHRCYP1A2 | |
| SCHEMBL7873282 | 0.85 | MTNR1A (0.56) | MCL1DAOALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL9987683 | 0.82 | MCL1 (0.45) | MCL1DAOALDH1A1TSHRCYP1A2 | |
| SCHEMBL30234519 | 0.82 | MCL1 (0.45) | MCL1DAOALDH1A1TSHRCYP1A2 | |
| SCHEMBL4542678 | 0.82 | MCL1 (0.57) | MCL1DAOALDH1A1TSHRCYP1A2 | |
| SCHEMBL30310709 | 0.82 | MCL1 (0.57) | MCL1DAOALDH1A1TSHRCYP1A2 | |
| SCHEMBL5265082 | 0.82 | MCL1 (0.53) | MCL1DAOALDH1A1TSHRCYP1A2 | |
| SCHEMBL914929 | 0.81 | DAO (0.57) | MCL1DAOALDH1A1TSHRCYP1A2 | |
| SCHEMBL2458550 | 0.80 | NOD2 (0.62) | MCL1ALDH1A1TSHRSMN1; SMN2MTNR1A | |
| SCHEMBL22396277 | 0.79 | DAO (0.54) | MCL1DAOALDH1A1TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111349039-A | Preparation method of indole-2-formic acid derivative | 浙江工业大学 | 2020-06-30 | — | — | CN | disclosed |
| US-9447105-B2 | Triazine compounds and a process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-09-20 | — | — | US | disclosed |
| US-20150353566-A1 | TRIAZINE COMPOUNDS AND A PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-12-10 | — | — | US | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |
| EP-1874317-A2 | PREPARATION AND USE OF ARYL ALKYL ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | Bayer Pharmaceuticals Corporation (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006113919-A2 | ARYL ALKYL ACID DERIVATIVES FOR AND USE THEREOF | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-10-26 | — | — | WO | disclosed |
| EP-1451185-A1 | INDOLE-2-CARBOXAMIDES AS FACTOR XA INHIBITORS | Aventis Pharma Deutschland GmbH (DE) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003044014-A1 | INDOLE-2-CARBOXAMIDES AS FACTOR XA INHIBITORS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353566-A1 | TRIAZINE COMPOUNDS AND A PROCESS FOR PREPARATION THEREOF | TPH2, IDO2, INMT | MCL1 1727/4885DAO 982/4885ALDH1A1 2885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.