Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9987910 | 1.00 | BLM (0.57) | BLMTSHRNPSR1LMNAMAPK1 | |
| SCHEMBL11477826 | 0.84 | LMNA (0.50) | BLMTSHRNPSR1LMNAMAPK1 | |
| SCHEMBL11477818 | 0.84 | LMNA (0.50) | BLMTSHRNPSR1LMNAMAPK1 | |
| SCHEMBL29881886 | 0.82 | BLM (0.62) | BLMTSHRNPSR1LMNAMAPK1 | |
| SCHEMBL43826 | 0.82 | BLM (0.62) | BLMTSHRNPSR1LMNAMAPK1 | |
| SCHEMBL29935536 | 0.82 | BLM (0.62) | BLMTSHRNPSR1LMNAMAPK1 | |
| SCHEMBL28135952 | 0.82 | BLM (0.62) | BLMTSHRNPSR1LMNAMAPK1 | |
| SCHEMBL10085813 | 0.82 | BLM (0.62) | BLMTSHRNPSR1LMNAMAPK1 | |
| SCHEMBL43825 | 0.82 | BLM (0.62) | BLMTSHRNPSR1LMNAMAPK1 | |
| SCHEMBL10786647 | 0.80 | BLM (0.61) | BLMTSHRNPSR1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431750-B2 | Preparation of hydroxyaromatic aldehydes | RHODIA OPERATIONS (FR) | 2013-04-30 | — | — | US | claimed |
| US-20110306802-A1 | PREPARATION OF HYDROXYAROMATIC ALDEHYDES | SPECIALTY OPERATIONS FRANCE (FR) | 2011-12-15 | — | — | US | claimed |
| US-8431750-B2 | Preparation of hydroxyaromatic aldehydes | RHODIA OPERATIONS (FR) | 2013-04-30 | — | — | US | disclosed |
| US-20110306802-A1 | PREPARATION OF HYDROXYAROMATIC ALDEHYDES | SPECIALTY OPERATIONS FRANCE (FR) | 2011-12-15 | — | — | US | disclosed |
| US-4163759-A | Process for preparing aromatic hydroxyaldehydes | HAARMANN & REIMER GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110306802-A1 | PREPARATION OF HYDROXYAROMATIC ALDEHYDES | AOX1, ALDH2, ALDH1A1 | BLM 1541/4885TSHR 4450/4885NPSR1 3112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.