Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.52 |
| ▸ | PGR | P06401 | 12/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 10/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1680240 | 0.91 | NR3C1 (0.57) | NR3C1PGRNR3C2CYP3A4KCNH2 | |
| SCHEMBL9987961 | 0.88 | NR3C1 (0.65) | NR3C1PGRNR3C2CYP3A4KCNH2 | |
| SCHEMBL292562 | 0.82 | NR3C1 (0.73) | NR3C1PGRNR3C2CYP3A4 | |
| SCHEMBL1680239 | 0.80 | NR3C1 (0.69) | NR3C1PGRNR3C2CYP3A4KCNH2 | |
| SCHEMBL293094 | 0.76 | NR3C1 (0.70) | NR3C1PGRNR3C2CYP3A4 | |
| SCHEMBL292807 | 0.76 | NR3C1 (0.82) | NR3C1PGRNR3C2CYP3A4KCNH2 | |
| SCHEMBL9987160 | 0.76 | NR3C1 (0.52) | NR3C1PGRNR3C2 | |
| SCHEMBL292934 | 0.76 | NR3C1 (0.72) | NR3C1PGRNR3C2CYP3A4 | |
| SCHEMBL9987170 | 0.75 | NR3C1 (0.75) | NR3C1PGRNR3C2CYP3A4KCNH2 | |
| SCHEMBL6383343 | 0.74 | NR3C1 (0.76) | NR3C1PGRNR3C2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397140-A1 | Compositions and methods for treating or preventing glaucoma or progression thereof | BAUSCH & LOMB INCORPORATED (US) | 2011-12-21 | — | — | EP | disclosed |