SCHEMBL998823

SCHEMBL998823

[c]1ccccc1Sc1ccon1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2423602 0.73
SCHEMBL28879727 0.73
SCHEMBL295632 0.70 EHMT2 (0.48)
SCHEMBL15610445 0.68 LMNA (0.36)
SCHEMBL1463082 0.68
SCHEMBL3145825 0.68 GRM5 (0.33)
SCHEMBL1119600 0.67
SCHEMBL1462116 0.67
SCHEMBL5058342 0.67 RXFP1 (0.41)
SCHEMBL237661 0.66 HPGD (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2872474-A2 ANTHRAQUINONE ANALOGS AND METHODS OF MAKING AND USING THEREOF Georgia State University Research Foundation, Inc. (US) 2015-05-20 EP claimed
WO-2014011753-A2 ANTHRAQUINONE ANALOGS AND METHODS OF MAKING AND USING THEREOF GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2014-01-16 WO claimed
JP-4829449-B2 2011-12-07 JP claimed
EP-1027056-B1 ALPHA-KETOAMIDE MULTICATALYTIC PROTEASE INHIBITORS CEPHALON INC (US) 2009-02-25 EP claimed
US-20050059722-A1 Substituted indazoles, compositions containing them, method of production and use AVENTIS PHARMA S.A. (FR) 2005-03-17 US claimed
JP-2003508353-A 2003-03-04 JP claimed
EP-0668860-B1 PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES UPJOHN CO (US) 2002-09-11 EP claimed
EP-1208097-A2 SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS Aventis Pharmaceuticals Inc. (US) 2002-05-29 EP claimed
WO-2001007436-A2 SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS AVENTIS PHARMACEUTICALS INC. (US) 2001-02-01 WO claimed
WO-1994011361-A1 PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES THE UPJOHN COMPANY (US) 1994-05-26 WO claimed
US-8957097-B2 Hemi-phorboxazole A derivatives and methods of their use THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2015-02-17 US disclosed
US-20130030027-A1 HEMI-PHORBOXAZOLE A DERIVATIVES AND METHODS OF THEIR USE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-01-31 US disclosed
WO-2011011665-A1 HEMI-PHORBOXAZOLE A DERIVATIVES AND METHODS OF THEIR USE THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2011-01-27 WO disclosed
EP-1027056-B1 ALPHA-KETOAMIDE MULTICATALYTIC PROTEASE INHIBITORS CEPHALON INC (US) 2009-02-25 EP disclosed
US-20060069037-A1 Peptide-containing alpha-ketoamide cysteine and serine protease inhibitors CEPHALON, INC. (US) 2006-03-30 US disclosed
US-6096778-A A PEPTIDE DERIVATIVE USEFUL FOR THE TREATMENT OF MUSCLE WASTING DISORDERS CEPHALON, INC. (US) 2000-08-01 US disclosed
EP-1021199-A1 PEPTIDE-CONTAINING $g(a)-KETOAMIDE CYSTEINE AND SERINE PROTEASE INHIBITORS CEPHALON, INC. (US) 2000-07-26 EP disclosed
WO-1999017778-A1 α-KETOAMIDE MULTICATALYTIC PROTEASE INHIBITORS CEPHALON INC. (US) 1999-04-15 WO disclosed
WO-1999017790-A1 PEPTIDE-CONTAINING α-KETOAMIDE CYSTEINE AND SERINE PROTEASE INHIBITORS CEPHALON INC. (US) 1999-04-15 WO disclosed
WO-1994011361-A1 PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES THE UPJOHN COMPANY (US) 1994-05-26 WO disclosed