SCHEMBL295632

SCHEMBL295632

[c]1ccccc1Sc1ccccn1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 1/20 0.48
EHMT1 Q9H9B1 1/20 0.48
APOBEC3G Q9HC16 1/20 0.48
L3MBTL1 Q9Y468 3/20 0.46
ALDH1A1 P00352 5/20 0.42
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
USP2 O75604 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
GAA P10253 2/20 0.42
MAPT P10636 2/20 0.42
HPGD P15428 1/20 0.42
KDM4E B2RXH2 3/20 0.39
LMNA P02545 3/20 0.39
HTT P42858 2/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
TSHR P16473 2/20 0.37
TDP1 Q9NUW8 1/20 0.35
PDE7A Q13946 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL995920 0.80 HSD17B10 (0.35) EHMT2EHMT1APOBEC3GL3MBTL1KMT2A
SCHEMBL2423602 0.76
SCHEMBL301719 0.76 EHMT2 (0.70) EHMT2EHMT1APOBEC3GL3MBTL1ALDH1A1
SCHEMBL4280312 0.76 EHMT2 (0.47) EHMT2EHMT1APOBEC3GL3MBTL1ALDH1A1
SCHEMBL3145825 0.74 GRM5 (0.33)
SCHEMBL10891052 0.74 EHMT2 (0.67) EHMT2EHMT1APOBEC3GL3MBTL1ALDH1A1
Hydrochloric Acid SCHEMBL28385922 0.74 EHMT2 (0.67) EHMT2EHMT1APOBEC3GL3MBTL1ALDH1A1
SCHEMBL1100503 0.72 HPGD (0.57) L3MBTL1ALDH1A1KMT2ANPSR1GAA
SCHEMBL3145115 0.71 DDAH1 (0.50) ALDH1A1MEN1KMT2AMAPTLMNA
SCHEMBL4612723 0.71 L3MBTL1 (0.61) EHMT2EHMT1APOBEC3GL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 425 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240074310-A1 LIGHT-EMITTING DEVICE, AND DISPLAY APPARATUS AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-02-29 US claimed
US-20220216419-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2022-07-07 US claimed
CN-113518805-A Photoinitiator 意大利艾坚蒙树脂有限公司 2021-10-19 CN claimed
US-9688645-B2 Macrocyclic urea and sulfamide derivatives as inhibitors of TAFIa SANOFI (FR) 2017-06-27 US claimed
US-20160251324-A1 MACROCYCLIC UREA AND SULFAMIDE DERIVATIVES AS INHIBITORS OF TAFIA SANOFI-AVENTIS (FR) 2016-09-01 US claimed
EP-2226319-B1 Process for the preparation of 2-(2-aminopyrimidin-4-yl)-1H-indol-5-carbonic acid derivatives SANOFI SA (FR) 2016-03-16 EP claimed
EP-2520568-B1 Spirocyclic nitriles as inhibitors of protease SANOFI SA (FR) 2015-09-09 EP claimed
EP-2240486-B1 TRIAZOLIUM SALTS AS PAR1 INHIBITORS, THEIR MANUFACTURE AND THEIR APPLICATION AS MEDICINE SANOFI SA (FR) 2015-09-09 EP claimed
EP-2104497-B1 SULFAMIDE DERIVATIVES AS TAFIA INHIBITORS SANOFI SA (FR) 2015-02-25 EP claimed
EP-2558465-B1 TRICYCLIC PYRIDYL-VINYL-PYROLES AS PAR1 INHIBITORS SANOFI SA (FR) 2014-12-17 EP claimed
US-20050004166-A1 Imino acid derivatives as inhibitors of matrix metalloproteinases AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2005-01-06 US claimed
EP-1474147-A1 PYRIMIDINE-BASED COMPOUNDS USEFUL AS GSK-3 INHIBITORS Vertex Pharmaceuticals Incorporated (US) 2004-11-10 EP claimed
WO-2004060874-A1 IMINO ACID DERIVATIVES FOR USE AS INHIBITORS OF MATRIX METALLOPROTEINASES AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2004-07-22 WO claimed
US-6753415-B2 BACTERICIDES AGAINST GRAMPOSITIVE AND GRAMNEGATIVE BACTERIA AND MACROLIDE RESISTANT BACTERIA ENANTA PHARMACEUTICALS, INC. 2004-06-22 US claimed
US-20040077646-A1 Indole nitriles ROCHE PALO ALTO LLC 2004-04-22 US claimed
US-20030212010-A1 23-O-substituted 5-O-mycaminosyltylonide derivatives ENANTA PHARMACEUTICALS, INC. 2003-11-13 US claimed
WO-2003089446-A2 23-O-SUBSTITUTED 5-O-MYCAMINOSYLTYLONIDE DERIVATIVES ENANTA PHARMACEUTICALS, INC. (US) 2003-10-30 WO claimed
US-20030199526-A1 Pyrimidine-based compounds useful as GSK-3 inhibitors VERTEX PHARMACEUTICALS, INCORPORATED 2003-10-23 US claimed
WO-2003049739-A1 PYRIMIDINE-BASED COMPOUNDS USEFUL AS GSK-3 INHIBITORS VERTEX PHARMACEUTICALS, INC. (US) 2003-06-19 WO claimed
US-5696243-A HEAT AND OXIDATION RESISTANCE GASF AKTIENGESELLSCHAFT (DE) 1997-12-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030212010-A1 23-O-substituted 5-O-mycaminosyltylonide derivatives OSTC, OGT, O60361 EHMT2 4852/4885EHMT1 4816/4885APOBEC3G 3315/4885
US-20050004166-A1 Imino acid derivatives as inhibitors of matrix metalloproteinases MMP9, MMP1, MMP25 EHMT2 4432/4885EHMT1 4127/4885APOBEC3G 1237/4885
US-20030199526-A1 Pyrimidine-based compounds useful as GSK-3 inhibitors GSK3B, GSK3A, GSKIP EHMT2 2694/4885EHMT1 2195/4885APOBEC3G 1349/4885
US-20040077646-A1 Indole nitriles TPH1, IDO1, NAT1 EHMT2 3300/4885EHMT1 2007/4885APOBEC3G 2476/4885
US-20160251324-A1 MACROCYCLIC UREA AND SULFAMIDE DERIVATIVES AS INHIBITORS OF TAFIA TFPI, TFPI2, SERPINC1 EHMT2 3541/4885EHMT1 3141/4885APOBEC3G 2178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.