Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.76 |
| ▸ | HTR7 | P34969 | 5/20 | 0.69 |
| ▸ | HTR1A | P08908 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10976043 | 0.90 | MAPT (0.82) | MAPTLMNANPSR1HTR7HTR1A | |
| SCHEMBL30528252 | 0.90 | MAPT (0.86) | MAPTLMNANPSR1HTR7HTR1A | |
| SCHEMBL3299369 | 0.86 | MAPT (0.70) | MAPTLMNANPSR1HTR7HTR1A | |
| SCHEMBL9987526 | 0.85 | KMT2A (0.68) | MAPTLMNAHTR7HTR1AMEN1 | |
| SCHEMBL28135156 | 0.85 | MAPT (0.78) | MAPTLMNANPSR1HTR7HTR1A | |
| SCHEMBL27786793 | 0.85 | MAPT (0.78) | MAPTLMNANPSR1HTR7HTR1A | |
| SCHEMBL4352910 | 0.84 | MEN1 (0.79) | MAPTNPSR1HTR7HTR1AMEN1 | |
| SCHEMBL12047642 | 0.84 | MAPT (0.61) | MAPTLMNANPSR1HTR7HTR1A | |
| SCHEMBL8210319 | 0.83 | MAPT (0.76) | MAPTLMNANPSR1HTR7HTR1A | |
| SCHEMBL12282092 | 0.83 | MAPT (0.76) | MAPTLMNANPSR1HTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383631-B2 | 1,6-disubstituted-3-amino-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-C]pyridin-7-one compounds and preparation thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-02-26 | — | — | US | disclosed |
| US-20110319619-A1 | NOVEL 1,6-DISUBSTITUTED-3-AMINO-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[3,4-C]PYRIDIN-7-ONE COMPOUNDS AND PREPARATION THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-12-29 | — | — | US | disclosed |
| US-3933824-A | Piperazinobutyrophenone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319619-A1 | NOVEL 1,6-DISUBSTITUTED-3-AMINO-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[3,4-C]PYRIDIN-7-ONE COMPOUNDS AND PREPARATION THEREOF | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, THPO, PLEC | MAPT 1257/4885LMNA 1772/4885NPSR1 4566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.