Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4237279 | 0.74 | CHRM5 (0.34) | SIGMAR1OPRD1 | |
| SCHEMBL28716337 | 0.74 | LMNA (0.45) | LMNACA12CA1CA2CA3 | |
| SCHEMBL28706411 | 0.74 | LMNA (0.45) | LMNACA12CA1CA2CA3 | |
| SCHEMBL4058738 | 0.73 | OPRD1 (0.33) | SIGMAR1OPRD1 | |
| SCHEMBL27667325 | 0.71 | SIGMAR1 (0.44) | CA12CA1CA2CA9SIGMAR1 | |
| SCHEMBL4236955 | 0.69 | SIGMAR1 (0.43) | CA12CA1CA2CA9SIGMAR1 | |
| SCHEMBL1494478 | 0.69 | SIGMAR1 (0.43) | SIGMAR1OPRD1 | |
| SCHEMBL7590414 | 0.69 | SIGMAR1 (0.43) | SIGMAR1OPRD1 | |
| SCHEMBL6422237 | 0.69 | SIGMAR1 (0.40) | LMNASIGMAR1OPRD1 | |
| SCHEMBL22360609 | 0.69 | SIGMAR1 (0.43) | CA1CA2SIGMAR1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |