Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 9/20 | 0.56 |
| ▸ | RXRA | P19793 | 7/20 | 0.55 |
| ▸ | RXRB | P28702 | 7/20 | 0.55 |
| ▸ | RXRG | P48443 | 7/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988678 | 0.92 | RXRA (0.54) | MALT1RXRARXRBRXRG | |
| SCHEMBL9988373 | 0.92 | MALT1 (0.54) | MALT1RXRARXRBRXRGABCB1 | |
| SCHEMBL9990151 | 0.91 | RXRA (0.52) | MALT1RXRARXRBRXRGCYP11B1 | |
| SCHEMBL9988498 | 0.91 | RXRA (0.51) | MALT1RXRARXRBRXRGCYP11B1 | |
| SCHEMBL9989579 | 0.87 | RXRA (0.52) | MALT1RXRARXRBRXRG | |
| SCHEMBL9988903 | 0.87 | RXRA (0.48) | MALT1RXRARXRBRXRG | |
| SCHEMBL9989681 | 0.84 | RXRA (0.48) | MALT1RXRARXRBRXRG | |
| SCHEMBL9988822 | 0.84 | MALT1 (0.54) | MALT1RXRARXRBRXRGALOX5 | |
| SCHEMBL9988512 | 0.84 | MALT1 (0.57) | MALT1RXRARXRBRXRGALOX5 | |
| SCHEMBL9988395 | 0.83 | MALT1 (0.55) | MALT1RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |