Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.48 |
| ▸ | RXRB | P28702 | 2/20 | 0.48 |
| ▸ | RXRG | P48443 | 2/20 | 0.48 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | ILK | Q13418 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988500 | 0.93 | RXRA (0.47) | RXRARXRBRXRGMALT1MAPK1 | |
| SCHEMBL9990096 | 0.88 | LMNA (0.47) | RXRARXRBRXRGMALT1KDM4E | |
| SCHEMBL9990151 | 0.87 | RXRA (0.52) | RXRARXRBRXRGMALT1CA1 | |
| SCHEMBL9988498 | 0.86 | RXRA (0.51) | RXRARXRBRXRGMALT1CA1 | |
| SCHEMBL9988373 | 0.86 | MALT1 (0.54) | RXRARXRBRXRGMALT1KDM4E | |
| SCHEMBL9989059 | 0.84 | MALT1 (0.56) | RXRARXRBRXRGMALT1 | |
| SCHEMBL9988903 | 0.83 | RXRA (0.48) | RXRARXRBRXRGMALT1KDM4E | |
| SCHEMBL9989579 | 0.83 | RXRA (0.52) | RXRARXRBRXRGMALT1CA1 | |
| SCHEMBL9988678 | 0.83 | RXRA (0.54) | RXRARXRBRXRGMALT1 | |
| SCHEMBL9989045 | 0.82 | RXRA (0.47) | RXRARXRBRXRGMALT1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |