Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | MDM4 | O15151 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP12 | P39900 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989103 | 1.00 | PPARA (0.42) | PPARAMDM4MDM2PPARGMGLL | |
| SCHEMBL1774142 | 0.90 | PPARA (0.50) | PPARAMDM4MDM2PPARGFOLH1 | |
| SCHEMBL9989812 | 0.90 | PPARA (0.50) | PPARAMDM4MDM2PPARGFOLH1 | |
| SCHEMBL9989804 | 0.89 | CHRM3 (0.48) | MDM4MDM2MEN1KMT2AALDH1A1 | |
| SCHEMBL9989802 | 0.89 | CHRM3 (0.48) | MDM4MDM2MEN1KMT2AALDH1A1 | |
| SCHEMBL9989472 | 0.86 | NLRP3 (0.43) | PPARAMDM4MDM2PPARGMEN1 | |
| SCHEMBL9989473 | 0.86 | NLRP3 (0.43) | PPARAMDM4MDM2PPARGMEN1 | |
| SCHEMBL9989446 | 0.81 | PPARA (0.46) | PPARAMDM4MDM2PPARGFOLH1 | |
| SCHEMBL9989444 | 0.81 | PPARA (0.46) | PPARAMDM4MDM2PPARGFOLH1 | |
| SCHEMBL9990118 | 0.79 | CHRM3 (0.42) | PPARAMDM4MDM2PPARGFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011159781-A2 | BITTER TASTE MODULATORS | SENOMYX, INC. (US) | 2011-12-22 | — | — | WO | disclosed |