Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989802 | 1.00 | CHRM3 (0.48) | CHRM3POLBNPC1RAB9AKDM4E | |
| SCHEMBL9989100 | 0.89 | PPARA (0.42) | MEN1KMT2AALDH1A1MDM4MDM2 | |
| SCHEMBL9989103 | 0.89 | PPARA (0.42) | MEN1KMT2AALDH1A1MDM4MDM2 | |
| SCHEMBL1774142 | 0.88 | PPARA (0.50) | POLBMEN1KMT2AALDH1A1MDM4 | |
| SCHEMBL9989812 | 0.88 | PPARA (0.50) | POLBMEN1KMT2AALDH1A1MDM4 | |
| SCHEMBL9989473 | 0.84 | NLRP3 (0.43) | TACR1MEN1KMT2AALDH1A1MDM4 | |
| SCHEMBL9989472 | 0.84 | NLRP3 (0.43) | TACR1MEN1KMT2AALDH1A1MDM4 | |
| SCHEMBL17492041 | 0.84 | MTNR1A (0.50) | POLBKDM4EKMT2ATDP1ALDH1A1 | |
| SCHEMBL17492043 | 0.84 | MTNR1A (0.50) | POLBKDM4EKMT2ATDP1ALDH1A1 | |
| SCHEMBL9989446 | 0.80 | PPARA (0.46) | POLBNPC1RAB9AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011159781-A2 | BITTER TASTE MODULATORS | SENOMYX, INC. (US) | 2011-12-22 | — | — | WO | disclosed |