Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989472 | 1.00 | NLRP3 (0.43) | NLRP3TACR1MAOBCTSSFFAR1 | |
| SCHEMBL9989103 | 0.86 | PPARA (0.42) | CTSSFFAR1FFAR4PPARAMDM4 | |
| SCHEMBL9989100 | 0.86 | PPARA (0.42) | CTSSFFAR1FFAR4PPARAMDM4 | |
| SCHEMBL1774142 | 0.85 | PPARA (0.50) | CTSSPPARAMDM4MDM2LMNA | |
| SCHEMBL9989812 | 0.85 | PPARA (0.50) | CTSSPPARAMDM4MDM2LMNA | |
| SCHEMBL9989804 | 0.84 | CHRM3 (0.48) | TACR1MDM4MDM2MEN1ALDH1A1 | |
| SCHEMBL9989802 | 0.84 | CHRM3 (0.48) | TACR1MDM4MDM2MEN1ALDH1A1 | |
| SCHEMBL17491970 | 0.83 | GPR34 (0.44) | NLRP3VNN1LMNAGPR34MEN1 | |
| SCHEMBL17491972 | 0.83 | GPR34 (0.44) | NLRP3VNN1LMNAGPR34MEN1 | |
| SCHEMBL17492142 | 0.78 | MMP2 (0.44) | MAOBLMNAMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011159781-A2 | BITTER TASTE MODULATORS | SENOMYX, INC. (US) | 2011-12-22 | — | — | WO | disclosed |