Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | RXRB | P28702 | 1/20 | 0.55 |
| ▸ | RXRG | P48443 | 1/20 | 0.55 |
| ▸ | RPA1 | P27694 | 1/20 | 0.54 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | CCKAR | P32238 | 10/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | FABP3 | P05413 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9990297 | 0.92 | CCKAR (0.55) | RXRARXRBRXRGRPA1MALT1 | |
| SCHEMBL9988397 | 0.90 | CACNA1G (0.56) | RXRARXRBRXRGRPA1MALT1 | |
| SCHEMBL9988340 | 0.90 | RXRA (0.59) | RXRARXRBRXRGRPA1MALT1 | |
| SCHEMBL9989355 | 0.89 | MALT1 (0.62) | RXRARXRBRXRGRPA1MALT1 | |
| SCHEMBL9988790 | 0.88 | RXRA (0.56) | RXRARXRBRXRGRPA1MALT1 | |
| SCHEMBL9988568 | 0.88 | RXRA (0.52) | RXRARXRBRXRGRPA1MALT1 | |
| SCHEMBL9989050 | 0.87 | CCKAR (0.58) | RXRARXRBRXRGRPA1MALT1 | |
| SCHEMBL9988686 | 0.86 | CCKAR (0.56) | RXRARXRBRXRGMALT1ALOX5 | |
| SCHEMBL9990003 | 0.86 | CCKAR (0.54) | RXRARXRBRXRGMALT1ALOX5 | |
| SCHEMBL9988493 | 0.85 | MALT1 (0.56) | RXRARXRBRXRGRPA1MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |