Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 13/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | RXRA | P19793 | 2/20 | 0.52 |
| ▸ | RXRB | P28702 | 2/20 | 0.52 |
| ▸ | RXRG | P48443 | 2/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989582 | 0.95 | ALOX5 (0.53) | CCKARALOX5PTGS2RXRARXRB | |
| SCHEMBL9990297 | 0.95 | CCKAR (0.55) | CCKARALOX5PTGS2RXRARXRB | |
| SCHEMBL9989267 | 0.89 | CCKAR (0.47) | CCKARALOX5PTGS2RXRARXRB | |
| SCHEMBL9990003 | 0.87 | CCKAR (0.54) | CCKARALOX5PTGS2RXRARXRB | |
| SCHEMBL9988507 | 0.86 | ALDH1A1 (0.45) | CCKARALOX5PTGS2RXRARXRB | |
| SCHEMBL9989126 | 0.86 | RXRA (0.55) | CCKARALOX5PTGS2RXRARXRB | |
| SCHEMBL9989603 | 0.86 | MALT1 (0.60) | CCKARALOX5PTGS2RXRARXRB | |
| SCHEMBL9990184 | 0.85 | CCKAR (0.51) | CCKARALOX5PTGS2RXRARXRB | |
| SCHEMBL9988502 | 0.85 | CCKAR (0.43) | CCKARALOX5PTGS2RXRARXRB | |
| SCHEMBL9988906 | 0.85 | CCKAR (0.53) | CCKARALOX5PTGS2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |