Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
| ▸ | CCKAR | P32238 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989011 | 0.91 | RXRA (0.48) | RXRARXRBRXRGLMNATP53 | |
| SCHEMBL9989578 | 0.90 | RXRA (0.47) | RXRARXRBRXRGLMNATP53 | |
| SCHEMBL9988490 | 0.90 | LMNA (0.49) | RXRARXRBRXRGLMNATP53 | |
| SCHEMBL9990141 | 0.89 | RXRA (0.51) | RXRARXRBRXRGLMNATP53 | |
| SCHEMBL9989656 | 0.88 | MALT1 (0.53) | RXRARXRBRXRGLMNATP53 | |
| SCHEMBL9988536 | 0.86 | RXRA (0.48) | RXRARXRBRXRGLMNATP53 | |
| SCHEMBL9988463 | 0.85 | RXRA (0.54) | RXRARXRBRXRGLMNATP53 | |
| SCHEMBL9988567 | 0.85 | MALT1 (0.55) | RXRARXRBRXRGLMNATP53 | |
| SCHEMBL9988474 | 0.85 | RXRA (0.51) | RXRARXRBRXRGLMNATP53 | |
| SCHEMBL9993178 | 0.85 | RXRA (0.47) | RXRARXRBRXRGLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |