SCHEMBL998934

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL312885	0.87	MAPT (0.35)	MAPTALDH1A1GAAPOLBMEN1
	SCHEMBL313693	0.86	CTSS (0.38)	MAPTALDH1A1GAAPOLBMEN1
	SCHEMBL314499	0.85	MAPT (0.35)	MAPTALDH1A1GAAPOLBMEN1
	SCHEMBL995496	0.85	ALDH1A1 (0.35)	MAPTALDH1A1GAAPOLBMEN1
	SCHEMBL12658415	0.85	MAPT (0.35)	MAPTALDH1A1GAAPOLBMEN1
	SCHEMBL8141690	0.78	NPC1 (0.31)	RAB9ANPC1
	SCHEMBL1954615	0.78	CTSS (0.32)	CTSS
	SCHEMBL10265556	0.77	CTSS (0.37)	MAPTALDH1A1GAAPOLBMEN1
	SCHEMBL1952055	0.77	—	—
	SCHEMBL13757338	0.77	MAPT (0.36)	MAPTALDH1A1GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.