Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.44 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166071 | 0.85 | ALDH1A1 (0.42) | MAPTGPR52LMNATP53EPHB4 | |
| SCHEMBL167233 | 0.82 | ALDH1A1 (0.47) | MAPTGPR52LMNAEPHB4MEN1 | |
| SCHEMBL5592945 | 0.78 | MAPT (0.50) | MAPTLMNACHEK1TP53EPHB4 | |
| SCHEMBL165141 | 0.78 | ALDH1A1 (0.42) | MAPTGPR52LMNAEPHB4MEN1 | |
| SCHEMBL15077844 | 0.74 | MAPT (0.41) | MAPTGPR52LMNATP53EPHB4 | |
| SCHEMBL5593101 | 0.72 | MAPT (0.43) | MAPTLMNACHEK1TP53EPHB4 | |
| SCHEMBL3707818 | 0.71 | ALDH1A1 (0.46) | MAPTLMNAEPHB4MEN1KMT2A | |
| SCHEMBL256206 | 0.71 | ALDH1A1 (0.57) | MAPTLMNAMEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL3699244 | 0.71 | ALDH1A1 (0.45) | MAPTLMNAEPHB4MEN1KMT2A | |
| SCHEMBL8118613 | 0.70 | MAPT (0.50) | MAPTLMNACHEK1TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397478-A1 | 1,3-diaryl substituted ureas as modulators of kinase activity. | CGI Pharmaceuticals, Inc. (US) | 2011-12-21 | — | — | EP | disclosed |