Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 9/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988823 | 0.88 | RXRA (0.43) | CCKARHTR7ALOX5PTGS2RXRA | |
| SCHEMBL9989267 | 0.87 | CCKAR (0.47) | CCKARALOX5PTGS2RXRARXRB | |
| SCHEMBL9990088 | 0.87 | RXRA (0.45) | HTR7ALOX5PTGS2RXRARXRB | |
| SCHEMBL9988490 | 0.83 | LMNA (0.49) | CCKARALOX5PTGS2RXRARXRB | |
| SCHEMBL9988521 | 0.83 | TP53 (0.42) | HTR7ALOX5PTGS2RXRARXRB | |
| SCHEMBL9988533 | 0.83 | LMNA (0.49) | ALOX5PTGS2RXRARXRBRXRG | |
| SCHEMBL9990073 | 0.83 | RXRA (0.48) | CCKARALOX5PTGS2RXRARXRB | |
| SCHEMBL9989011 | 0.83 | RXRA (0.48) | CCKARALOX5PTGS2RXRARXRB | |
| SCHEMBL9988516 | 0.81 | RXRA (0.48) | CCKARALOX5PTGS2RXRARXRB | |
| SCHEMBL9988639 | 0.81 | RXRA (0.46) | CCKARALOX5PTGS2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |