Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | RXRA | P19793 | 2/20 | 0.49 |
| ▸ | RXRB | P28702 | 2/20 | 0.49 |
| ▸ | RXRG | P48443 | 2/20 | 0.49 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.48 |
| ▸ | CCKAR | P32238 | 10/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989053 | 0.95 | ALOX5 (0.55) | ALOX5PTGS2RXRARXRBRXRG | |
| SCHEMBL9988785 | 0.94 | MALT1 (0.51) | ALOX5PTGS2RXRARXRBRXRG | |
| SCHEMBL9988906 | 0.93 | CCKAR (0.53) | ALOX5PTGS2RXRARXRBRXRG | |
| SCHEMBL9989578 | 0.91 | RXRA (0.47) | ALOX5PTGS2RXRARXRBRXRG | |
| SCHEMBL9989546 | 0.89 | MALT1 (0.55) | ALOX5PTGS2RXRARXRBRXRG | |
| SCHEMBL9990241 | 0.87 | TP53 (0.45) | ALOX5PTGS2RXRARXRBRXRG | |
| SCHEMBL9988534 | 0.87 | MALT1 (0.55) | ALOX5PTGS2RXRARXRBRXRG | |
| SCHEMBL9989639 | 0.85 | ALOX5 (0.55) | ALOX5PTGS2RXRARXRBRXRG | |
| SCHEMBL9989582 | 0.85 | ALOX5 (0.53) | ALOX5PTGS2RXRARXRBRXRG | |
| SCHEMBL9989603 | 0.84 | MALT1 (0.60) | ALOX5PTGS2RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |