Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | RPA1 | P27694 | 4/20 | 0.53 |
| ▸ | RXRA | P19793 | 2/20 | 0.53 |
| ▸ | RXRB | P28702 | 2/20 | 0.53 |
| ▸ | RXRG | P48443 | 2/20 | 0.53 |
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.51 |
| ▸ | CCKAR | P32238 | 4/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988911 | 0.92 | ALOX5 (0.56) | ALOX5PTGS2RPA1RXRARXRB | |
| SCHEMBL9988474 | 0.91 | RXRA (0.51) | ALOX5PTGS2RPA1RXRARXRB | |
| SCHEMBL9989053 | 0.89 | ALOX5 (0.55) | ALOX5PTGS2RXRARXRBRXRG | |
| SCHEMBL9988534 | 0.88 | MALT1 (0.55) | ALOX5PTGS2RPA1RXRARXRB | |
| SCHEMBL9988937 | 0.87 | RXRA (0.47) | ALOX5PTGS2RPA1RXRARXRB | |
| SCHEMBL9989607 | 0.85 | ALOX5 (0.51) | ALOX5PTGS2RXRARXRBRXRG | |
| SCHEMBL9990205 | 0.85 | RXRA (0.46) | ALOX5PTGS2RPA1RXRARXRB | |
| SCHEMBL9989121 | 0.85 | RXRA (0.52) | ALOX5PTGS2RPA1RXRARXRB | |
| SCHEMBL9988906 | 0.83 | CCKAR (0.53) | ALOX5PTGS2RXRARXRBRXRG | |
| SCHEMBL9988571 | 0.83 | ALOX5 (0.52) | ALOX5PTGS2RPA1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |