Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 14/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15615640 | 0.79 | POLB (0.42) | PKM | |
| SCHEMBL9989670 | 0.76 | KDM4E (0.61) | OPRD1OPRM1KDM4EPKM | |
| SCHEMBL27536506 | 0.75 | SIGMAR1 (0.46) | SIGMAR1OPRD1OPRM1CHRM5CHRM3 | |
| SCHEMBL5958440 | 0.74 | CA2 (0.42) | SIGMAR1CHRM5CHRM3 | |
| SCHEMBL6678936 | 0.74 | SIGMAR1 (0.58) | SIGMAR1OPRD1OPRM1CHRM5CHRM3 | |
| Hydrochloric Acid SCHEMBL26617092 | 0.73 | CA2 (0.41) | SIGMAR1CHRM5CHRM3 | |
| SCHEMBL2110264 | 0.71 | SIGMAR1 (0.42) | SIGMAR1OPRD1OPRM1CHRM5CHRM3 | |
| SCHEMBL10770619 | 0.71 | SIGMAR1 (0.44) | SIGMAR1OPRD1OPRM1CHRM5CHRM3 | |
| SCHEMBL13484571 | 0.71 | SIGMAR1 (0.44) | SIGMAR1OPRD1CHRM5CHRM3 | |
| SCHEMBL7591281 | 0.71 | SIGMAR1 (0.44) | SIGMAR1OPRD1OPRM1CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |