Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9990035 | 0.76 | SIGMAR1 (0.43) | KDM4EPKMOPRD1OPRM1 | |
| SCHEMBL4039571 | 0.75 | KMT2A (0.64) | KMT2AMEN1ALDH1A1POLBNPC1 | |
| SCHEMBL6605312 | 0.75 | HTR2C (0.47) | KMT2AMEN1ALDH1A1OPRD1SLC6A2 | |
| SCHEMBL12251783 | 0.74 | HPGD (0.72) | HPGDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL4369147 | 0.73 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1OPRD1SLC6A2 | |
| SCHEMBL4869220 | 0.72 | OPRD1 (0.53) | KDM4EKMT2AMEN1ALDH1A1OPRD1 | |
| SCHEMBL1007950 | 0.71 | HPGD (0.68) | HPGDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL3220549 | 0.71 | HPGD (0.68) | HPGDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL21538629 | 0.71 | HPGD (0.68) | HPGDKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL1007948 | 0.71 | HPGD (0.68) | HPGDKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |