Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 14/20 | 0.48 |
| ▸ | NPC1 | O15118 | 12/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.48 |
| ▸ | PKM | P14618 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28198975 | 0.76 | RAB9A (0.53) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| SCHEMBL827403 | 0.74 | RAB9A (0.67) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| SCHEMBL5637618 | 0.74 | RAB9A (0.53) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| SCHEMBL9533462 | 0.73 | RAB9A (0.56) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| SCHEMBL19279180 | 0.73 | RAB9A (0.51) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| Hydrogen Sulfide SCHEMBL16859912 | 0.72 | RAB9A (0.64) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| Hydrogen Sulfide SCHEMBL28205214 | 0.72 | RAB9A (0.64) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| Methane SCHEMBL28056221 | 0.72 | RAB9A (0.64) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| 2-Phenylbenzo[D]Thiazole SCHEMBL28209257 | 0.71 | RAB9A (0.58) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| SCHEMBL29474819 | 0.69 | RAB9A (0.81) | RAB9ANPC1KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076337-B2 | Antitumoral derivatives of ET-743 | PHARMA MAR, S.A. (ES) | 2011-12-13 | — | — | US | claimed |