Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.62 |
| ▸ | HTR2A | P28223 | 7/20 | 0.62 |
| ▸ | HTR1A | P08908 | 2/20 | 0.62 |
| ▸ | ACHE | P22303 | 2/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | HTR7 | P34969 | 5/20 | 0.60 |
| ▸ | HTR6 | P50406 | 5/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.57 |
| ▸ | DRD1 | P21728 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | HRH1 | P35367 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9995324 | 0.99 | DRD2 (0.63) | DRD2HTR2AHTR1AACHESLC6A4 | |
| SCHEMBL9995066 | 0.97 | DRD2 (0.63) | DRD2HTR2AHTR1AACHESLC6A4 | |
| SCHEMBL9994993 | 0.93 | DRD2 (0.70) | DRD2HTR2AHTR1AACHESLC6A4 | |
| SCHEMBL9995021 | 0.92 | ACHE (0.66) | DRD2HTR2AHTR1AACHESLC6A4 | |
| SCHEMBL9995295 | 0.90 | ACHE (0.66) | DRD2HTR2AHTR1AACHESLC6A4 | |
| SCHEMBL9994937 | 0.87 | DRD2 (0.63) | DRD2HTR2AHTR1AACHESLC6A4 | |
| SCHEMBL792615 | 0.85 | DRD2 (0.70) | DRD2HTR2AHTR1AACHESLC6A4 | |
| SCHEMBL9995246 | 0.85 | DRD2 (0.58) | DRD2HTR2AHTR1AACHESLC6A4 | |
| SCHEMBL8887811 | 0.85 | KCNH2 (0.59) | DRD2HTR2AHTR1AACHESLC6A4 | |
| SCHEMBL9995262 | 0.83 | ACHE (0.62) | DRD2HTR2AACHESLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110306638-A1 | BENZISOXAZOLE PIPERIDINYL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS COMPRISING THE DERIVATIVES AND THEIR USE | NHWA PHARMA. CORPORATION (CN) | 2011-12-15 | — | — | US | claimed |
| US-20110306638-A1 | BENZISOXAZOLE PIPERIDINYL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS COMPRISING THE DERIVATIVES AND THEIR USE | NHWA PHARMA. CORPORATION (CN) | 2011-12-15 | — | — | US | disclosed |
| US-20110306638-A1 | BENZISOXAZOLE PIPERIDINYL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS COMPRISING THE DERIVATIVES AND THEIR USE | NHWA PHARMA. CORPORATION (CN) | 2011-12-15 | — | — | US | disclosed |
| US-20110306638-A1 | BENZISOXAZOLE PIPERIDINYL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS COMPRISING THE DERIVATIVES AND THEIR USE | NHWA PHARMA. CORPORATION (CN) | 2011-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110306638-A1 | BENZISOXAZOLE PIPERIDINYL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS COMPRISING THE DERIVATIVES AND THEIR USE | HTR2A, HTR2C, HTR5A | DRD2 75/4885HTR2A 1/4885HTR1A 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.