Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.68 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 6/20 | 0.48 |
| ▸ | CA2 | P00918 | 6/20 | 0.48 |
| ▸ | CA9 | Q16790 | 5/20 | 0.48 |
| ▸ | CA5A | P35218 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA6 | P23280 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3168222 | 0.97 | ACHE (0.65) | ACHETEAD4TDP1ALDH1A1MAPT | |
| SCHEMBL9015590 | 0.84 | ACHE (0.68) | ACHETEAD4TDP1ALDH1A1MAPT | |
| Sulfuric Acid SCHEMBL6839879 | 0.84 | ACHE (0.68) | ACHETEAD4TDP1ALDH1A1MAPT | |
| SCHEMBL11887 | 0.83 | — | — | |
| SCHEMBL8469646 | 0.83 | ACHE (1.00) | ACHETEAD4TDP1ALDH1A1MAPT | |
| SCHEMBL29225799 | 0.82 | ACHE (0.65) | ACHETEAD4TDP1ALDH1A1MAPT | |
| Sulfamate SCHEMBL28135386 | 0.82 | ACHE (0.65) | ACHETEAD4TDP1ALDH1A1MAPT | |
| Formaldehyde SCHEMBL8164998 | 0.80 | ACHE (0.81) | ACHETEAD4TDP1ALDH1A1MAPT | |
| SCHEMBL16451469 | 0.80 | HTR6 (0.76) | ACHETDP1ALDH1A1MAPTCA1 | |
| SCHEMBL3838022 | 0.80 | HTR6 (0.76) | ACHETDP1ALDH1A1MAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8333985-B2 | Non-glycerol stabilized bone graft | WARSAW ORTHOPEDIC, INC. (US) | 2012-12-18 | — | — | US | claimed |
| US-20070178158-A1 | Stabilized bone graft | WARSAW ORTHOPEDIC, INC. | 2007-08-02 | — | — | US | claimed |
| JP-2007519496-A | — | — | 2007-07-19 | — | — | JP | claimed |
| EP-1708651-A1 | STABILIZED BONE GRAFT | Osteotech, Inc., (US) | 2006-10-11 | — | — | EP | claimed |
| WO-2005072656-A1 | STABILIZED BONE GRAFT | OSTEOTECH, INC. (US) | 2005-08-11 | — | — | WO | claimed |
| EP-1434608-A2 | IMPROVED BONE GRAFT | Osteotech, Inc. (US) | 2004-07-07 | — | — | EP | claimed |
| US-20030143258-A1 | Bone graft | WARSAW ORTHOPEDIC, INC. | 2003-07-31 | — | — | US | claimed |
| WO-2003030956-A2 | IMPROVED BONE GRAFT | OSTEOTECH, INC. (US) | 2003-04-17 | — | — | WO | claimed |
| US-10357511-B2 | Bone matrix compositions and methods | WARSAW ORTHOPEDIC, INC. (US) | 2019-07-23 | — | — | US | disclosed |
| US-10328179-B2 | Bone matrix compositions and methods | WARSAW ORTHOPEDIC, INC. (US) | 2019-06-25 | — | — | US | disclosed |
| EP-1434608-B1 | IMPROVED BONE GRAFT | WARSAW ORTHOPEDIC INC (US) | 2018-08-22 | — | — | EP | disclosed |
| US-20170296581-A1 | BONE MATRIX COMPOSITIONS AND METHODS | WARSAW ORTHOPEDIC INC (US) | 2017-10-19 | — | — | US | disclosed |
| EP-3207948-A1 | BONE MATRIX COMPOSITIONS AND METHODS | Warsaw Orthopedic, Inc. (US) | 2017-08-23 | — | — | EP | disclosed |
| US-9717822-B2 | Bone matrix compositions and methods | WARSAW ORTHOPEDIC, INC. (US) | 2017-08-01 | — | — | US | disclosed |
| US-20030143258-A1 | Bone graft | WARSAW ORTHOPEDIC, INC. | 2003-07-31 | — | — | US | disclosed |
| WO-2003030956-A2 | IMPROVED BONE GRAFT | OSTEOTECH, INC. (US) | 2003-04-17 | — | — | WO | disclosed |
| US-6410704-B1 | NUCLEOTIDE SEQUENCES CODING ENZYMATIC POLYPEPTIDE FOR USE IN TREATMENT OF VIRAL DISEASE | ARCH DEVELOPMENT CORPORATION | 2002-06-25 | — | — | US | disclosed |
| EP-0514830-B1 | Use of a herpes protease | ARCH DEV CORP (US) | 2000-05-03 | — | — | EP | disclosed |
| US-5478727-A | Identifying enzyme inhibitor; detecting viral infections | ARCH DEVELOPMENT CORPORATION (US) | 1995-12-26 | — | — | US | disclosed |
| EP-0514830-A2 | Methods and compositions of a preparation and use of a herpes protease | ARCH DEVELOPMENT CORPORATION (US) | 1992-11-25 | — | — | EP | disclosed |