Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGAM1 | P18669 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CCR2 | P41597 | 12/20 | 0.55 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1104715 | 0.81 | CCR2 (0.67) | CCR2 | |
| SCHEMBL1104716 | 0.81 | CCR2 (0.54) | PGAM1CCR2MEP1B | |
| SCHEMBL17599364 | 0.80 | PGAM1 (0.55) | PGAM1MEN1KMT2AGAALMNA | |
| SCHEMBL170277 | 0.79 | CCR2 (0.60) | PGAM1LMNACCR2TSHR | |
| SCHEMBL9996881 | 0.78 | ALDH1A1 (0.62) | MEN1KMT2AGAALMNASLC25A1 | |
| SCHEMBL9997073 | 0.78 | HSD17B10 (0.59) | MEN1KMT2ACCR2TSHRMEP1B | |
| SCHEMBL305993 | 0.77 | CYP2C9 (0.61) | CCR2TSHR | |
| SCHEMBL13510516 | 0.77 | EP300 (0.65) | PGAM1CCR2TSHR | |
| SCHEMBL307486 | 0.77 | CYP2C9 (0.63) | CCR2 | |
| SCHEMBL10223335 | 0.77 | CYP2C9 (0.61) | CCR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161201-A1 | BISARYLSULFONAMIDES USEFUL AS KINASE INHIBITORS IN THE TREATMENT OF INFLAMMATION AND CANCER | KANCERA AB (SE) | 2011-12-29 | — | — | WO | disclosed |