Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | SLC16A3 | O15427 | 7/20 | 0.44 |
| ▸ | SLC16A1 | P53985 | 7/20 | 0.44 |
| ▸ | MCTS1 | Q9ULC4 | 3/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CCKAR | P32238 | 8/20 | 0.42 |
| ▸ | ILK | Q13418 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | RPA1 | P27694 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9998393 | 0.89 | RXRA (0.46) | RXRARXRBRXRGSLC16A3SLC16A1 | |
| SCHEMBL9998657 | 0.84 | RXRA (0.50) | RXRARXRBRXRGSLC16A3SLC16A1 | |
| SCHEMBL9989578 | 0.82 | RXRA (0.47) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL9999152 | 0.81 | CCKAR (0.49) | RXRARXRBRXRGSLC16A3SLC16A1 | |
| SCHEMBL9998809 | 0.80 | CCKAR (0.45) | RXRARXRBRXRGSLC16A3SLC16A1 | |
| SCHEMBL9999143 | 0.80 | RXRA (0.69) | RXRARXRBRXRGSLC16A3SLC16A1 | |
| SCHEMBL9989656 | 0.80 | MALT1 (0.53) | RXRARXRBRXRGSLC16A3SLC16A1 | |
| SCHEMBL9989011 | 0.80 | RXRA (0.48) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL9998637 | 0.79 | CCKAR (0.47) | RXRARXRBRXRGALOX5PTGS2 | |
| SCHEMBL9988966 | 0.79 | MAPT (0.51) | RXRARXRBRXRGALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161645-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |