Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | CCKAR | P32238 | 7/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9989011 | 0.86 | RXRA (0.48) | MAPTMEN1KMT2ARXRARXRB | |
| SCHEMBL9988490 | 0.84 | LMNA (0.49) | MAPTRXRARXRBRXRGCCKAR | |
| SCHEMBL9999143 | 0.83 | RXRA (0.69) | RXRARXRBRXRGCCKARALOX5 | |
| SCHEMBL9989267 | 0.83 | CCKAR (0.47) | MAPTRXRARXRBRXRGCCKAR | |
| SCHEMBL9990141 | 0.82 | RXRA (0.51) | MAPTMEN1KMT2ARXRARXRB | |
| SCHEMBL9998572 | 0.82 | CCKAR (0.51) | MAPTHPGDRXRARXRBRXRG | |
| SCHEMBL9989578 | 0.82 | RXRA (0.47) | MEN1KMT2ARXRARXRBRXRG | |
| SCHEMBL9989656 | 0.82 | MALT1 (0.53) | MAPTRXRARXRBRXRGCCKAR | |
| SCHEMBL9990073 | 0.81 | RXRA (0.48) | RXRARXRBRXRGCCKARALOX5 | |
| SCHEMBL9989266 | 0.81 | RXRA (0.46) | MEN1KMT2ARXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |