Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 13/20 | 0.55 |
| ▸ | RXRA | P19793 | 2/20 | 0.51 |
| ▸ | RXRB | P28702 | 2/20 | 0.51 |
| ▸ | RXRG | P48443 | 2/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.45 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.45 |
| ▸ | MCTS1 | Q9ULC4 | 2/20 | 0.45 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9998530 | 0.90 | CCKAR (0.57) | CCKARRXRARXRBRXRGALOX5 | |
| SCHEMBL9998637 | 0.88 | CCKAR (0.47) | CCKARRXRARXRBRXRGALOX5 | |
| SCHEMBL9999066 | 0.86 | CCKAR (0.49) | CCKARRXRARXRBRXRGALOX5 | |
| SCHEMBL9998771 | 0.86 | ALOX5 (0.55) | CCKARRXRARXRBRXRGALOX5 | |
| SCHEMBL9998570 | 0.84 | CCKAR (0.51) | CCKARRXRARXRBRXRGALOX5 | |
| SCHEMBL9998578 | 0.83 | RXRA (0.49) | CCKARRXRARXRBRXRGALOX5 | |
| SCHEMBL9988463 | 0.83 | RXRA (0.54) | CCKARRXRARXRBRXRGALOX5 | |
| SCHEMBL9996784 | 0.83 | RXRA (0.49) | CCKARRXRARXRBRXRGALOX5 | |
| SCHEMBL9998572 | 0.82 | CCKAR (0.51) | CCKARRXRARXRBRXRGALOX5 | |
| SCHEMBL9988871 | 0.81 | RXRA (0.53) | CCKARRXRARXRBRXRGALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161645-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |