Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | RXRA | P19793 | 3/20 | 0.53 |
| ▸ | RXRB | P28702 | 3/20 | 0.53 |
| ▸ | RXRG | P48443 | 3/20 | 0.53 |
| ▸ | CCKAR | P32238 | 10/20 | 0.52 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.48 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.48 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9996784 | 0.94 | RXRA (0.49) | ALOX5PTGS2RXRARXRBRXRG | |
| SCHEMBL9998572 | 0.93 | CCKAR (0.51) | ALOX5PTGS2RXRARXRBRXRG | |
| SCHEMBL9998587 | 0.86 | CCKAR (0.55) | ALOX5PTGS2RXRARXRBRXRG | |
| SCHEMBL9998530 | 0.85 | CCKAR (0.57) | ALOX5PTGS2RXRARXRBRXRG | |
| SCHEMBL9998570 | 0.84 | CCKAR (0.51) | ALOX5PTGS2RXRARXRBRXRG | |
| SCHEMBL9998797 | 0.83 | RXRA (0.49) | ALOX5PTGS2RXRARXRBRXRG | |
| SCHEMBL9998578 | 0.83 | RXRA (0.49) | ALOX5PTGS2RXRARXRBRXRG | |
| SCHEMBL9988871 | 0.82 | RXRA (0.53) | ALOX5PTGS2RXRARXRBRXRG | |
| SCHEMBL9989306 | 0.82 | RXRA (0.52) | ALOX5PTGS2RXRARXRBRXRG | |
| SCHEMBL9999066 | 0.81 | CCKAR (0.49) | ALOX5PTGS2RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161645-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |
| WO-2011161645-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |