Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | PAM | P19021 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733958 | 0.86 | PAM (0.46) | ALDH1A1PAMMAPK1L3MBTL1CES2 | |
| SCHEMBL2254547 | 0.81 | ALDH1A1 (0.60) | ALDH1A1PAMMAPK1L3MBTL1CES2 | |
| SCHEMBL9997729 | 0.81 | ALDH1A1 (0.55) | ALDH1A1PAMMAPK1L3MBTL1CES2 | |
| SCHEMBL9997727 | 0.81 | ALDH1A1 (0.55) | ALDH1A1PAMMAPK1L3MBTL1CES2 | |
| SCHEMBL4884398 | 0.80 | CNR2 (0.40) | ALDH1A1L3MBTL1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL4874815 | 0.80 | SMN1; SMN2 (0.43) | ALDH1A1L3MBTL1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL18295996 | 0.75 | ALDH1A1 (0.43) | ALDH1A1MAPK1L3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL161364 | 0.74 | ALDH1A1 (0.50) | ALDH1A1CES2CES1TSHRSMN1; SMN2 | |
| SCHEMBL17928599 | 0.74 | ALDH1A1 (0.63) | ALDH1A1PAMMAPK1L3MBTL1CES2 | |
| SCHEMBL8046342 | 0.74 | ALDH1A1 (0.50) | ALDH1A1PAMMAPK1L3MBTL1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8558012-B2 | 2-fluoro-1,3-benzodithiol 1,1,3,3-tetraoxide derivative, production method thereof, and production method of monofluoromethyl group-containing compound using the same | NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2013-10-15 | — | — | US | disclosed |
| US-20110319637-A1 | 2-FLUORO-1,3-BENZODITHIOL 1,1,3,3-TETRAOXIDE DERIVATIVE, PRODUCTION METHOD THEREOF, AND PRODUCTION METHOD OF MONOFLUOROMETHYL GROUP-CONTAINING COMPOUND USING THE SAME | NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2011-12-29 | — | — | US | disclosed |
| US-20080064624-A1 | Organoleptic Compounds and Their Use in Perfume Compositions | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2008-03-13 | — | — | US | disclosed |
| US-20080064624-A1 | Organoleptic Compounds and Their Use in Perfume Compositions | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319637-A1 | 2-FLUORO-1,3-BENZODITHIOL 1,1,3,3-TETRAOXIDE DERIVATIVE, PRODUCTION METHOD THEREOF, AND PRODUCTION METHOD OF MONOFLUOROMETHYL GROUP-CONTAINING COMPOUND USING THE SAME | CBR1, CYP1B1, CYP2F1 | ALDH1A1 160/4885PAM 1298/4885MAPK1 1707/4885 |
| US-20080064624-A1 | Organoleptic Compounds and Their Use in Perfume Compositions | CPT1A, CYP2E1, TRPA1 | ALDH1A1 378/4885PAM 957/4885MAPK1 4224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.