Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9998969 | 0.91 | ESR1 (0.43) | ESR1HPGDMAPTLMNAPOLB | |
| SCHEMBL173483 | 0.80 | ALDH1A1 (0.49) | HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11531 | 0.79 | LMNA (0.52) | ESR1HPGDMAPTLMNAPOLB | |
| SCHEMBL20308881 | 0.77 | ESR1 (0.44) | ESR1HPGDMAPTLMNAMEN1 | |
| SCHEMBL20264528 | 0.75 | ALDH1A1 (0.47) | ESR1MAPTLMNAHSD17B10MEN1 | |
| SCHEMBL29940280 | 0.75 | ALDH1A1 (0.47) | ESR1MAPTLMNAHSD17B10MEN1 | |
| SCHEMBL10941845 | 0.72 | ESR1 (0.49) | ESR1HPGDLMNAPOLBSMN1; SMN2 | |
| SCHEMBL30994793 | 0.72 | ESR1 (0.49) | ESR1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11250 | 0.70 | ALDH1A1 (0.51) | ESR1HPGDMAPTPOLBHSD17B10 | |
| SCHEMBL4286533 | 0.70 | ESR1 (0.48) | ESR1LMNAPOLBSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230413824-A1 | AGROCHEMICAL COMPOSITION COMPRISING 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS AND USE THEREOF | PI INDUSTRIES LTD. (IN) | 2023-12-28 | — | — | US | disclosed |
| US-20170223959-A1 | FUNGICIDAL PYRAZOLES | FMC CORPORATION | 2017-08-10 | — | — | US | disclosed |
| US-9655361-B2 | Fungicidal pyrazoles | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-05-23 | — | — | US | disclosed |
| US-20150230467-A1 | FUNGICIDAL PYRAZOLES | FMC CORPORATION | 2015-08-20 | — | — | US | disclosed |
| US-9062005-B2 | Fungicidal pyrazoles | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-06-23 | — | — | US | disclosed |
| US-20110319430-A1 | FUNGICIDAL PYRAZOLES | E.I. DU PONT NEMOURS AND COMPANY (US) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319430-A1 | FUNGICIDAL PYRAZOLES | CBR3, CBR1, CYP2S1 | ESR1 1798/4885HPGD 1675/4885MAPT 4737/4885 |
| US-20230413824-A1 | AGROCHEMICAL COMPOSITION COMPRISING 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS AND USE THEREOF | CBR3, PFAS, PAH | ESR1 3369/4885HPGD 3364/4885MAPT 2467/4885 |
| US-20150230467-A1 | FUNGICIDAL PYRAZOLES | CBR3, CBR1, CYP2S1 | ESR1 1798/4885HPGD 1675/4885MAPT 4737/4885 |
| US-20170223959-A1 | FUNGICIDAL PYRAZOLES | CBR3, CBR1, CYP2S1 | ESR1 1798/4885HPGD 1675/4885MAPT 4737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.